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國立臺北科技大學 學術資源網

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LI-CHU TSAI

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Professor/Department of Molecular Science and Engineering
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Journal articles

  • "Opto Field-Effect Transistors for Detecting Quercetin–Cu2+ Complex", Sensors, 22, 7219, 2022/09, SCI
  • "Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming", Pharmacological Research, 178, 106148(1-8頁), 2022/04, SCI
  • "A dual function electro-optical silicon field-effect transistor molecular sensor", Journal of Materials Chemistry C, 9, 14286-14293, 2021/09, SCI
  • "Crystal structures of the GH6 Orpinomyces sp. Y102 CelC7 enzyme with exo and endo activity and its complex with cellobiose", Acta Crystallographic Section D STRUCTURAL BIOLOGY, 75, 12, 1138-1147, 2019/12, SCI
  • "Development of mutlifunctional nanoparticles self-assembled from trimethyl chitosan and fucoidan for enhanced oral delivery of insulin", International Journal of Biological Macromolecules, 126, 141-150, 2019/04, SCI
  • "Synthesis and evaluation of antibacterial and antioxidant activity of small molecular chitosan–fucoidan conjugate nanoparticles", Res Chem Intermed, 44, 8, 4855–4871, 2018/08, SCI
  • "Detection of electrically neutral and nonpolar molecules in ionic solutions using silicon nanowires", Nanotechnology, 28, 16, 165501, 2017/04, SCI
  • "EGCG/gelatin-doxorubicin gold nanoparticles enhance therapeutic efficacy of doxorubicin for prostate cancer treatment", nanomedicine, 11, 1, 9-30, 2016/01, SCI
  • "Structures of exoglucanase from Clostridium cellulovorans: cellotetraose binding and cleavage", Acta Cryst. F, F71, 1264-1272, 2016/01, SCI
  • "A highly active beta-glucanase from a new strain of rumen fungus Orpinomyces sp.Y102 exhibits cellobiohydrolase and cellotriohydrolase activities", Bioresource Technology, 170, 513-521, 2014/10, SCI
  • "Improving Nanowire Sensing Capability by Electrical Field Alignment of Surface Probing Molecules", Nano letters, 13, 2564-2569, 2013/05, SCI
  • "纖維素水解與結構分析", Bioresource Technology, 123, 125-134, 2012/12, SCI
  • "Recovery Based Nanowire Field-Effect Transistor Detection of Pathogenic Avian Influenza DNA", Japanese Journal of Applied Physics, 51, 02BL02-1-5, 2012/02, SCI
  • "Structural basis for the inhibition of 1,3-1,4-Structural basis for the inhibition of 1,3-1,4-beta-D-glucanase by noncompetitive-D-glucanase by noncompetitive", Biochemical and Biophysical Research Communications, 407, 3, 593-598, 2011/04, SCI
  • "Formation of single-electron-transistors using self-assembly", J Nanopart Res, 12, 8, 2859-2864, 2010/10, SCI
  • "Structural and catalytic roles of amino acid residues located at substrate binding pocket in Fibrobacter succinogenes 1,3-1,4-??-D-glucanase", Proteins, 78, 13, 2820-2830, 2010/10, SCI
  • "Structural and catalytic roles of residues located in β13 strand and the following β-turn loop in Fibrobacter succinogenes 1,3-1,4-β- D –glucanase", Biochimica et Biophysica Acta, 1790, 231-239, 2009/02, SCI
  • "Mutational and structural studies of the active site residues in truncated Fibrobacter succinogenes 1,3-1,4-??-D-glucanase", Acta Crystallography, D64, 1259-1266, 2008/12, SCI
  • "Structural Modeling of Glucanase-Substrate Complexes Suggests A Conserved Tyrosine is involved in Carbohydrate Recognition in Plant 1,3-1,4-β-D-Glucanases", J Comput Aided Mol Des, 7, 6, 245-251, 2008/10, SCI
  • "Rationale for Differential Carbohydrate Recognition by Barley and Fibrobacter succinogenes 1,3-1,4-β-D-Glucanases", IEEE proceedings, 311-316, 2007/12, ELSE2
  • "Control and Detection of Organosilane Polarization on Nanowire Field-Effect Transistors", Nano Letters, 7, 12, 3656-3661, 2007/12, SCI
  • "Assembly of Nanoparticle Patterns with Single-Particle Resolution Using DNA-Mediated Charge Trapping Technique: Method and Applications", Advanced Functional Materials, 17, 3182-3186, 2007/08, SCI
  • "DNA as an Electron-Beam Sensitive Reagent for Nano-Patterning", Advanced materials, 18, 1517-1520, 2006/03, SCI
  • "Crystal Structure of Truncated Fibrobacter succinogenes 1,3-1,4-β-D-Glucanase in Complex with β-1,3-1,4-Cellotriose", Journal Molecular Biology, 354, 642~651, 2005/12, SCI
  • "Positioning of extended individual DNA molecules between electrodes by non-uniform AC electric fields", Nanotechnology, 16, 2738~2742, 2005/11, SCI
  • "DNA binding and cleavage by the periplasmic endonuclease Vvn from Vibrio Vulnificus: a novel structure with an old active site", EMBO, 22, 4014-4025, 2003/08, SCI
  • "Crystal structure of a natural jellyroll protein: circular-permutated 1,3-1,4-β-D-glucanase from Fibrobacter succinogenes", Journal Molecular Biology, 330, 607~620, 2003/07, SCI
  • "Metal ions and phosphate binding in the HNH motif: crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and Different Divalent Metal Ions", Protein Sci., 11, 2947-2957, 2002/10, SCI
  • "Mutagenesis of Trp54 and Trp203 residues on Fibrobacter succinogenes 1,3-1,4-β-D-glucanase significantly affects the enzyme’s catalytic activities", Biochemistry, 41, 8759-8766, 2002/07, SCI
  • "Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme", Protein Sci., 11, 332-341, 2002/02, SCI

Conference papers

  • "Detection of DNA hybridization by monitoring the change in the molecular permittivity using Field-Effect-Transistors", 2022化學年會, 台北, 2022/03/11
  • "Detecting the interaction between quercetin and CuCl2 by using Field Effect Transistors", 2021化學年會, 桃園, 2021/03/12
  • "Using Solution-Phase modified APTES on Silicon Dioxide at room temperature", 2021化學年會, 桃園, 2021/03/12
  • "Probing the surface potential of an electrode in an ionic solu-tion using the open-loop electric potential microscope (OL-EPM)", 2021化學年會, 桃園, 2021/03/12
  • "Detecting neutrophil gelatinase associated lipocalin (NGAL)", the 18th ACC, 台北, 2019/12/09
  • "Detecting Biomolecular interactions using Field Effect Transistors", 第 18 屆亞洲化學大會, 台北, 2019/12/08
  • "以延伸式閘極場效應電晶體檢測多巴胺與DNA適體之間的交互作用", 2018國際智慧感測器研討會, 台北, 2018/06/01
  • "以氧化石墨電子元件作為分子檢測平台之特性研究", 以氧化石墨電子元件作為分子檢測平台之特性研究, 台北, 2018/06/01
  • "以場效應電晶體作為化學反應吸收光譜", 2017 中國化學會年會, 嘉義, 2018/01/01
  • "Silicon nanowire field-effect-transistors (FETs) for detection of biologically active molecular interactions", HYBER Symposium 2017, Helsinki, 2017/05/18
  • "Functional and structural simulation analysis of Glycoside Hydrolase Family 3 β-glucosidase from Uncultured Neocallimastix frontalis J11", 第22屆生物物理研討會, 高雄義守大學, 2017/05/17
  • "以介電泳動操控生物分子並提升矽場效應電晶體的檢測效率", 106 物理年會, 台北, 2017/01/16
  • "以矽薄膜場效應電晶體偵測光致異構物之結構變化", 106 物理年會, 台北淡江大學, 2017/01/16
  • "Structural of GH6 Orpinomyces sp. Y102 enzyme reveals its flexible loops function as the cellobiohydrolase and cellotrihydrolase activity", 第 14屆亞洲結晶協會會議, 河內, 2016/12/04
  • "以矽薄膜場效電晶體偵測易揮發有機物氣體", 2016中國化學年會, 台中中興大學, 2016/12/03
  • "以介電泳動技術提升奈米矽線場效應電晶體之檢測效率", 2016中國化學年會, 台中中興大學, 2016/12/03
  • "Detection of histidine/Ni-NTA interaction in the physiological-pH environment using silicon nanowire field-effect-transistors", 6th International Conference on Materials and Applications for Sensors and Transducers, 雅典, 2016/09/27
  • "Detection of electrically neutral and nonpolar molecules in ionic solutions using silicon nanowire field effect transistors", 6th International Conference on Materials and Applications for Sensors and Transducers, 雅典, 2016/09/27
  • "Silicon nanowire field-effect-transistors for the detection of the biologically active molecular interactions", 第三次與大阪府立大學交流研討會, 大阪府立大學, 2016/09/05
  • "The structure and sequence analysis of glycoside hydrolase family 3 enzymes", 二十一屆生物物理年會, 新竹, 2016/05/19
  • "以矽奈米線元件檢測 F1-ATPase 與 ATP、ADP 相互作用", 104學年度師生聯合學術研究發表會, 2016/05/17
  • "EGCG/gelatin-doxorubicin gold nanoparticles enhance therapeutic efficacy of doxorubicin for prostate cancer treatment", 本校金手獎, 2016/04/20
  • "EGCG/gelatin-doxorubicin gold nanoparticles enhance therapeutic efficacy of doxorubicin for prostate cancer treatment", 本校金手獎, 2016/04/20
  • "以奈米矽線場效應電晶體偵測酵素與醣類 相互結合與催化作用", 臺北科技大學暨台北醫學大學 學術合作專題研究計畫期末成果發表, 臺北科技大學, 2015/06/05
  • "以奈米矽線場效應電晶體偵測酵素與 醣類的相互結合與催化作用", 103學年度師生聯合學術研究發表會, 臺北 臺北醫學大學, 2015/05/26
  • "特異性標靶發炎巨噬細胞之奈米粒子結合光動力與化學治療之抗炎研究", 台北科技大學(金手獎), 臺北科技大學, 2015/04/22
  • "Improving Nanowire Sensing Capability by Electrical Field Alignment of Surface Probing Molecules", 2014物理年會, 台中 中興大學, 2014/01/21
  • "Structural and functional study of the Eukaryotic Orpinomyces sp. Y102 OsCel6 catalytic domain C7", 2013 Asian Crystallographic Association Meeting (AsCA'13), hong kong, 2013/12/07
  • "大腸桿菌F1-ATPase的表現與活性測試", 2013化學年會, 南投 國立暨南國際大學, 2013/11/23
  • "Crystal Structure of the Eukaryotic Orpinomyces sp. Y102 GH6 Endoglucanase Cel6", 第十八屆生物物理研討會, 台北, 2013/06/27
  • "修飾茶多酚之奈米金應用於前列腺癌治療與成像", 台北科技大學(金手獎), 台北, 2013/06/25
  • "以奈米矽線場效應電晶體觀察糖水解功能", 第18屆化學感測器科技102年年會, 台北, 2013/06/01
  • "Detection of ATP synthase activated modified liposomes using silicon nanowire field-effect-transistors", 本校成果展, 台北, 2013/05/20
  • "以分子印跡技術及矽奈米線場效應電晶體偵測多巴胺", 本校成果展, 台北, 2013/05/20
  • "Caffeic acid-loaded chitosan/cellulose composite films as active packagings for β-carotene preservation", 台灣保健食品學會2012年會員大會暨�ヲ抳P過敏研討會, 高雄, 2013/03/23
  • "Detection of ATP induced proton pumping in F0F1-ATPase modified liposomes using silicon nanowire field-effect-transistors", 102 物理年會, 花蓮, 2013/01/29
  • "Improved Nanowire Sensors by Electrical Field Alignment of Surface Probing Molecules", 2013物理年會, 花蓮, 2013/01/29
  • "Structural modelling and kinetic studies for Uncultured Neocallimastigales 1,4-β-Dxylanase", 2012 AsCA, 阿得列德, 2012/12/02
  • "Detection of the interaction between enzyme and substrate by silicon nanowire field-effect-transistors", Taiwan-Mongolia Joint Symposium on Science Education, 烏蘭巴托, 2012/06/25
  • "外切型纖維素水解�悚獐甡懇硎c分析", 第十七屆生化工程研討會, 高雄, 2012/06/25
  • "Structural modeling and kinetic studies for xylanase, xynR8", 第十七屆生物物理聯合研討會 (The 17th Joint Biophysics Conference), 台北, 2012/05/23
  • "以奈米矽線場效應電晶體檢測偶氮苯芳香族衍生物的順式與反式結構", 本校金手獎, 台北, 2012/04/25
  • "醣水解�悅a族7和16結構和序列分析", 本校金手獎, 台北, 2012/04/25
  • "Detection of Pathogenic Avian Influenza DNA using Nanowire Field-Effect Transistors with Recoverable Probe DNA", 2012物理年會, 嘉義, 2012/01/17
  • "利用高靈敏度矽奈米細線場效應電晶體偵測光致順反異構物", 100年中國化學年會, 新竹, 2011/12/03
  • "Structural and functional studies of the active-sites in four glycoside hydrolase beta-jellyroll families", 第22屆國際結晶學會, 馬德里, 2011/08/22
  • "Structural and functional studies of the active-sites in four glycoside hydrolase beta-jellyroll families", 第十六屆生物物理聯合研討會 (The 15th Joint Biophysics Conference, 花蓮東華大學, 2011/05/18
  • "Nanowire-field-effect-transistor based molecular sensors with very high sensitivity", 2011物理年會, 台北, 2011/01/25
  • "Structural comparison of glycosyl hydrolase family 16 enzymes", 99年中國化學年會, 台北, 2010/11/03
  • "Structure and function of the Fibrobacter succinogenes 1,3-1,4-β-D-glucanase mutants F40I and W203F in complex with inhibitors", 第十屆亞洲結晶學會, 釜山, 2010/10/31
  • "Detection of Alcohol using Porphyrin Modified Silicon-Nanowire Field-Effect-Transistors", 98學年度師生聯合學術研究發表會 臺北醫學大學, 台北, 2010/05/31
  • "Crystal structure of Fibrobacter succinogenes 1,3-1,4-β-D-glucanase mutant W203F in complex with inhibitors", 98學年度師生聯合學術研究發表會, 台北, 2010/05/31
  • "Detection of Alcohol using Porphyrin Modified Silicon-Nanowire Field-Effect-Transistors", 第16屆化學感測器年會, 台北, 2010/05/23
  • "Crystal structure of Fibrobacter succinogenes 1,3-1,4-β-D-glucanase mutant W203F in complex with inhibitors", 第十五屆生物物理聯合研討會 (The 15th Joint Biophysics Conference, 台北, 2010/05/19
  • "1,3-1,4-β-D-葡聚醣水解酶突變種Trp203Phe的晶體結構與功能", 台北科技大學金手獎, 台北, 2010/04/09
  • "Detection of Alcohol using Porphyrin Modified Silicon-Nanowire Field-Effect-Transistors", National Taipei University of Technology-Okayama Univrsity, 台北, 2010/03/15
  • "Structural modeling studies at the active site of family 16 glycosyl hydrolases", National Taipei University of Technology-Okayama Univrsity, 台北, 2010/03/15
  • "Kinetic and Structural Studies of the Twelve Mutant Structures of Truncated Fibrobacter succinogenes 1,3-1,4-β-D-Glucanase", National Taipei University of Technology-Okayama Univrsity, 台北, 2010/03/15
  • "Detection of bio-molecular charge using silicon-on-insulator based nanowire field-effect-transistors", 99年物理年會, 台南, 2010/02/03
  • "Alcohol detection using iron-porphyrin modified silicon-nanowires field effect transistors", 2009台灣化學工程學會56週年年會暨國科會化學工程學門成果發表會, 台中, 2009/11/27
  • "Crystal structures of Fibrobacter succinogenes1,3-1,4-β-D-glucanase F40I and W203F mutants in complex with inhibitors", 分子生物研究所第一屆研究壁報展, 台北, 2009/07/10
  • "Crystal structures of Fibrobacter succinogenes 1,3-1,4-β-D-glucanase mutants in complex with inhibitors", 第十四屆生物物理聯合研討會, 台南成功大學, 2009/06/24
  • "Purification and characterization of a chimeric 1,3-1,4-β-D-glucanase and β-1,4-xylanase enzyme", 第十二屆美洲華人生物科學學會國際學術研討會, 台北中央研究院, 2009/06/14
  • "Detection of bio-molecular charge using silicon-on-insulator based nanowire field-effect-transistors", 98年的物理年會, 彰化, 2009/01/19
  • "Structures of Phe40Ile and Trp203Phe mutants of Fibrobacter succinogenes 1,3-1,4-β-D-glucanase reveal the importance of sugar-aromatic CH–pi stacking interactions", The 6th Asian Biophysical Association (ABA) Symposium, 香港, 2009/01/11
  • "Alignment of immobilized molecules with parallel electrical fields", 97化學年會, 彰化, 2008/12/05
  • "Mutagenesis and Structural Studies of the Substrate Binding Cavity of Truncated Fibrobacter succinogenes 1,3-1,4-β-D-Glucanase", 第十三屆生物物理新知研討會, 台中-惠蓀林場, 2008/05/21
  • "Surface Modification of Iron(II)-Porphyrin on Silicon Nanowires", Taiwan - Japan International Symposium on Organic Chemistry and Molecular Science, 台北, 2008/04/18
  • "Purification of GST-MyD88", Taiwan - Japan International Symposium on Organic Chemistry and Molecular Science, 台北, 2008/04/18
  • "Cloning and purification of a bifunctional fusion enzyme of 1,3-1,4-β-D-glucanase and β-1,4-xylanase", Taiwan - Japan International Symposium on Organic Chemistry and Molecular Science, 台北, 2008/04/18
  • "Rationale for Differential Carbohydrate Recognition by Barley and Fibrobacter succinogenes 1,3-1,4-β-D-Glucanases", FBIT 2007, 濟州島, 2007/10/11
  • "Over-expression and purification of GST-MyD88", 第十二屆生物物理新知研討會, 新竹, 2007/05/23
  • "農藥殘留檢測分析技術的探討", 95化學年會, 台北, 2006/11/24
  • "中草藥中腺苷之檢測方法確效", 中日, 台北, 2006/08/28
  • "1,3-1,4-β-D-葡聚醣水解酶突變種Glu85Ile的晶體結構", 94化學年會, 高雄, 2005/11/19
  • "腫瘤壞死因子受體結合因子TRAF6的純化與結晶", 94化學年會, 高雄中山大學, 2005/11/19
  • "DNA as an Electron-Beam Sensitive Reagent for Nano-Patterning", 第四屆海峽兩岸奈米科學與技術研討會, 雲南麗江, 2005/08/22
  • "Mutagenesis study of Fibrobacter succinogenes 1,3-1,4-β-D-Glucanase", 第十屆生物物理新知研討會, 清華大學生命科學系, 2005/05/24
  • "構築腫瘤壞死因子受體結合因子TRAF6序列與MyD88蛋白質表現與純化", 九十三年化學年會, 台中(中興大學), 2004/10/26
  • "Complex Structure of Lichenase and β-1,4-1,3-Cellotriose Reveals its Substrate Binding Conformation and Cleavage Mechanism", 九十三年化學年會, 台中 (中興大學), 2004/10/26
  • "葡聚醣水解和三糖複合體晶體結構", 九十二年化學年會, 2003/10/28
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