Professor／Department of Chemical Engineering and Biotechnology
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Journal articles
"A Comparative Study of Stone Re-Treatment after Lithotripsy.", Life, 2022, 12, 2130, 2022/12, SCI
"A Highly Sensitive Urinary Exosomal miRNAs Biosensor Applied to Evaluation of Prostate Cancer Progression.", bioengineering, 2022, 9, 803, 2022/12, SCI
"Urinary MicroRNA Sensing Using Electrochemical Biosensor to Evaluate Colorectal Cancer Progression", biomedicines, 10, 6, 1434, 2022/06, SCI
"EPA Modulates KLK Genes via miR-378: A Potential Therapy in Prostate Cancer", cancers, 14, -, 2813, 2022/06, SCI
"Micro-RNA378a-3p Induces Apoptosis in Sarcomatoid Renal Cell Carcinoma and Regulates POLR2A and RUNX2 Expression.", Anticancer Research, 42, (2):, 811-825., 2022/02, SCI
"Gain of TPPP as a predictor of progression in patients with bladder cancer", EXPERIMENTAL AND THERAPEUTIC MEDICINE, 22, (5):, 1204., 2021/11, SCI
"Glucose/Glutathione Co-triggered Tumor Hypoxia Relief and Chemodynamic Therapy to Enhance Photothermal Therapy in Bladder Cancer", ACS Appl Bio Mater ., 18;4, (10):, 7485-7496., 2021/10, SCI
"An Effective SARS-CoV-2 Electrochemical Biosensor with Modifiable Dual Probes Using a Modified Screen-Printed Carbon Electrode", Micromachines, 29;, 12(10):, 1171., 2021/09, SCI
"High-Sensitivity Dual-Probe Detection of Urinary miR-141 in Cancer Patients via a Modified Screen-Printed Carbon Electrode-Based Electrochemical Biosensor.", Sensors, 21, (9), 3183., 2021/05, SCI
"Low expression of PTEN with over-expressed phosphorylated AktSer473 and AktThr308 associated with poor overall survival in upper tract urothelial carcinoma.", Oncology Letters, (6), 20, 347, 2020/12, SCI
"Over-expression of TNNI3K is Associated with Early-stage Carcinogenesis of Cholangiocarcinoma", Molecular Carcinogenesis, 58, 2, 270-278, 2018/10, SCI
"Real-time circulating tumor cells detection via highly sensitive needle-like cytosensordemonstrated by a blood flow simulation", Biosensors and Bioelectronic, S0956-5663, (18), 30388-9, 2018/05, SCI
"EPA significantly improve anti-EGFR targeting therapy by regulating miR-378 expression in colorectal cancer", oncology letter, 16, 5, 6188-6194, 2018/05, SCI
"Electrochemical Detection of Norepinephrine Using Sponge-like Co3O4 Modified Screen Printed Carbon Electrode", International Journal of Electrochemical Science, 12, 2017, 10524 – 10533, 2017/10, SCI
"A Novel Flakes-Like Structure of Molybdenum Disulphide Modified Glassy Carbon Electrode for the Efficient Electrochemical Detection of Dopamine", Int. J. Electrochem. Sci, 12, (2017), 9288 – 9300, 2017/09, SCI
"Cabozantinib-induced osteoblast secretome promotes survival and migration of metastatic prostate cancer cells in bone", Oncotarget, Vol. 8, 2017, 74987-75006, 2017/08, SCI
"Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2", Science Translational Medicine, 9(378), 9, 6234-6342, 2017/02, SCI
"Label-Free Detection of AR-V7 mRNA in Prostate Cancer Using Yb2Ti2O7 –Based Electrolyte-Insulator-Semiconductor Biosensors", The Electrochemical Society, 2016. 163 (14) B1-B8., 163, (14), B710-B717, 2016/11, SCI
"Enzymatic Glucose Biosensor Based on TbY x O y Electrolyte-Insulator-Semiconductor", Journal of The Electrochemical Society 163 (8) B445-B452 (2016), 163, (8), B445-B452, 2016/06, SCI
"Genetic alterations of HER genes in chromophobe renal cell carcinoma", Oncol Lett., 11(3):, (3), 2111–2116., 2016/03, SCI
"Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression.", Oncol Rep., 35, (1), 107-16, 2016/01, SCI
"Genome-wide gene expression profiling of ischemia-reperfusion injury in rat kidney, intestine and skeletal muscle implicate a common involvement of MAPK signaling pathway", Molecular Medicine Reports, 11, 5, 3786-93, 2015/05, SCI
"Mutation Signatures Implicate Aristolochic Acid in Bladder Cancer Development", Genome Medicine, 2015, 7, 38, 2015/04, SCI
"Effect of Postdeposition Annealing on the Structural and Sensing Characteristics of Tb2O3 and Tb2Ti2O7 Sensing Films for Electrolyte-Insulator-Semiconductor pH Sensors", Journal of The Electrochemical Society, 162, 4, B83-B88, 2015/02, SCI
"Nanosized Particles Of Titanium Dioxide Specifically Increase The Efficiency Of Conventional Polymerase Chain Reaction.", Digest Journal of Nanomaterials and Biostructures, Vol. 8,, No. 4,, 1435 - 1445, 2014/10, SCI
"Impact of titanium content and postdeposition annealing on the structural and sensing properties of TbTixOy sensing membranes", Journal of Materials Chemistry C, 2014, 2, 7575-7582, 2014/07, SCI
"Combined Detection of Cancer Cells and a Tumor Biomarker using an Immunomagnetic Sensor for the Improvement of Prostate-Cancer Diagnosis.", Advanced Materials, Volume 26, Issue 22, 3662–3666, 2014/06, SCI
"Beware Imposters: MA-1, A Novel MALT Lymphoma Cell Line, Is Misidentified and Corresponds to Pfeiffer, A Diffuse Large B-Cell Lymphoma Cell Line—A Reply: Despite the Same 8-Code STR, MA-1 and Pfeiffer Are Cytogenetically Diverse", Genes Chromosomes Cancer., 53, (2), 211-3, 2014/02, SCI
"Aberrant expression of the PRAC gene in prostate cancer.", International Journal of Oncology, 43, (6), 1960-6, 2013/12, SCI
"Nanosized particles of titanium dioxide specifically increase the efficiency of conventional polymerase chain reaction", Digest Journal of Nanomaterials and Biostructures, 8, 4, 1435-1445, 2013/12, SCI
"Efficient expansion of mesenchymal stem cells from mouse bone marrow under hypoxic conditions", Journal of Tissue Engineering and Regenerative Medicine, 7, 12, 984-993, 2013/12, SCI
"cDNA microarray profiling of rat cholangiocarcinoma induced by thioacetamide.", Molecular Medicine Reports, 8, 2, 350-60, 2013/08, SCI
"Genome-wide mutational signatures of aristolochic Acid and its application as a screening tool.", Science Translational Medicine, 5, 197, 197ra101., 2013/08, SCI
"No evidence of IGH-MALT1-translocation in the Ma-1 cell line-A reply.", Genes Chromosomes Cancer, 52, (6), 593-4., 2013/06, SCI
"Role of TRPV1 and P2X receptors in the activation of lung vagal C-fiber afferents by inhaled cigarette smoke in rats.", Molecular Medicine Reports, 7, (4), 1300-4, 2013/04, SCI
"Simultaneous Detection of DNA Bases on Electrodes Chemically Modified with Graphene-New Fuchsin", Int. J. Electrochem. Sci., 8, 2013, 3963-3973, 2013/03, SCI
"High Performance GdTixOy Electrolyte-Insulator-Semiconductor pH Sensor and Biosensor", Int. J. Electrochem. Sci., 8, (2013), 606 - 620, 2013/01, SCI
"Efficient expansion of mesenchymal stem cells from mouse bone marrow under hypoxic conditions.", Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/, term.1491., 1491, 2012/05, SCI
"Establishment of a Novel MALT Lymphoma Cell Line, MA-1, From a Patient with t(14;18)(q32;q21)-Positive Helicobacter Pylori-Independent Gastric MALT Lymphoma", Genes, Chromosomes and Cancer, 50, (11), 908-21, 2011/11, SCI
"Phosphorylated T567ezrin is associated with merlin expression in KIT", Molecular Medicine Reports, 5, (1), 17-21, 2011/10, SCI
"Characterization of a novel rat cholangiocarcinoma cell culture model—CGCCA.", World J Gastroenterol., 17(24), 28, 2924-2932, 2011/06, SCI
"Molecular Characterization of Acquired Tolerance of Tumor cells to Picropodophyllin (PPP)", PLoS ONE, 14, 6 (3), e14757, 2011/03, SCI
"Neuregulin/erythroblastic leukemia viral oncogene homolog 3 autocrine loop contributes to invasion and early recurrence of human hepatoma.", Hepatology, 53, 2, 504-516, 2011/02, SCI
"New Sarcomatoid Cancer Cell Line SAR-HCV Established from a Hepatitis C Virus-related Liver Tumour Lesion", ANTICANCER RESEARCH, 31, 1, 129-37, 2011/01, SCI
"Identification of Genetic Alterations in Upper Urinary Tract Urothelial Carcinoma in End-Stage Renal Disease Patients", Genes, Chromosomes & Cancer, 49, 10, 928-34., 2010/10, SCI
"Expression of parvin beta is a prognostic factor for Patients with urothelial cell carcinoma of the upper urinary tract", British Journal of Cancer, 103, 6, 852-60, 2010/08, SCI
"Expression of ezrin is associated with invasion and dedifferentiation of hepatitis B related hepatocellular carcinoma", BMC Cancer, 15, 9(1), 233, 2009/07, SCI
"Thioredoxin-interacting protein: an oxidative-stress related gene is upregulated by glucose in human prostate carcinoma cells.", J Mol Endocrinol., 42, 3, 205-14, 2009/03, SCI
"A 10-year old girl with bifocal synovial sarcoma", The Lancet Oncology, 7, 7, 605-7, 2006/07, SCI
"Malignant cells exhibit limited resistance to the insulin-like growth factor receptor 1 inhibitor PPP", Oncogene, 22, 25, 3186-95, 2006/05, SCI
"Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer", Prostate, 2, 66, 157-72, 2006/02, SCI
"Prognostic impact of immunohistochemical expression of ezrin in highly malignant soft tissue sarcomas", Clin Cancer Res, 17, 11, 6189-204, 2005/09, SCI
"Immunophenotypic and molecular cytogenetic features of the cell line UP-LN1 established from a lymph node metastasis of a poorly-differentiated carcinoma", Anticancer Res, 2A, 25, 683-91, 2005/03, SCI
"Insulin-like growth factor type 1 receptor expression correlates to good prognosis in highly malignant soft tissue sarcoma", Clin Cancer Res, 1, 11, 206-16, 2005/01, SCI
"Molecular cytogenetic characterization of primary cultures and established cell lines from non-medullary thyroid tumors", Int J Oncol, 1, 26, 141-9, 2005/01, SCI
"Loss of chromosome 13q is a frequently acquired event in genetic progression of soft tissue sarcomas in the abdominal cavity", Int J Oncol, 1, 26, 5-16, 2005/01, SCI
"Characterization of large chromosome markers in a malignant fibrous histiocytoma by spectral karyotyping, comparative genomic hybridization (CGH), and array CGH", Cancer Genet Cytogenet, 1, 150, 27-32, 2004/04, SCI
"Evaluation of immunohistochemical parameters as prognostic markers in malignant fibrous histiocytoma", Oncology Report, 5, 10, 1641-5, 2003/09, SCI
"Gain of 17q in malignant fibrous histiocytoma is associated with a longer disease-free survival and a low risk of developing distant metastasis", Br J Cancer, 4, 89, 720-6, 2003/08, SCI
Books
Molecular Cytogenetic Studies of Soft Tissue Sarcoma: with focus on Prognosis and Acquired Events, Karolinska University Press, 91-7140-241-1, 2005/04/12
Molecular cytogenetic studies of soft tissue sarcomas, karolinska University Press, 91-7349-658-8, 2003/09/25
Conference papers
"Detection of circulating tumor cells using highly sensitive filamentous carbon fiber biosensors through blood flow simulation", 2024第38屆台灣生物化學及分子生物學學會, Taipei, 2024/03/23
"Detection of Urinary miRNA in Prostate Cancer by using microRNA based Biosensor", 2024 the 38th Join Annual conference of biomedical science灣生物化學及分子生物學學會, Taipei, 2024/03/23
"Development of a Nucleotide Tetrahedral Structure Silver Nanoparticles Biosensor", 2024 The 38th Join Annual Conference of Biomedical Science, Taipei, 2024/03/23
"Develop a Highly Selective, Sensitive, and Stable Silver Nanoparticle Biosensor for Detection of Urinary miRNA-21 in Prostate Cancer", 2023TWICE 台灣化學工程學會70周年年會, 台北, 2023/12/09
"Detection of circulating tumor cells using highly sensitive filamentous carbon fiber biosensors through blood flow simulation", 2023 TwIChE 台灣化學工程學會70週年年會暨國科會化學工程學門成果發表會/國際分子與生醫工程研討會, Taipei, 2023/12/09
"Is Treatment of Advanced Upper Tract Urothelial Carcinoma Comparable with Lower Tract?", 2023 KPS-APSU Joint International Symposium, Seoul, 2023/09/01
"miR-451 detection of electrochemical biosensor in urine for prostate cancer diagnosis and postoperative tracking", 生化醫學年會, 台中, 2022/10/22
"Identification of metastatic associated genes using novel paired primary and metastatic upper-tract urothelial carcinoma cell lines", UAA2022, 19th urclogical association of asia congress, Sydney, 2022/10/05
"The clinical significance of urinary miRNA-21 in the cancer patients and the development of microRNA biosensor", 2021 International Conference on Smart Sensors, Taipei, 2021/07/05
"Dual-probe detection of microRNA biosensor in urine for colorectal cancer diagnosis and postoperative tracking", 2021 BEST Conference & International Symposium on Biotechnology and Bioengineering (BEST 2021), Taichung City, TAIWAN,, 2021/06/25
"Screening of cancer patients’ urinary microRNA by using sandwich hybridization probes with SPCE biosensor", 台灣泌尿腫瘤醫學會半年會, Taipei, 2020/07/31
"The role and clinical value of Pol II, RNX2 and miR-378 in sarcomatoid renal cell carcinoma", 台北科技大學暨長庚紀念醫院學術合作專題研究暨化成果發表, Taipei, 2020/06/19
"The role of miR-378 in sarcomatoid renal cell carcinoma", The 26th Meeting of the EAU Section of Urological Research (ESUR), Porto, 2019/10/10
"Genetic alterations of enzalutamide and abiraterone acetate resistant prostate cancer", The 26th Meeting of the EAU Section of Urological Research (ESUR), Porto, 2019/10/10
"Potential urinary miRNA-141 as a biomarker for detection of prostate cancer by using screen printed carbon electrode based electrochemical microRNA sensor", The 26th Meeting of the EAU Section of Urological Research (ESUR), Porto, 2019/10/10
"The Emerging technology of Yb2Ti2O7 electrolyte-insulator-semiconductor biosensors for rapid screening of targeted mutation", American Association for Cancer Research Annual Meeting 2015, Philadelphia, PA., 2015/04/22
"A new prognostic marker- Interferon regulatory factor 6 in renal cell carcinoma ” /USA / (2015.04.21)", American Association for Cancer Research Annual Meeting 2015, Philadelphia, PA., 2015/04/22
"Using eicosapentaenoic acid to improve Cetuximab sensitivity in KRAS mutants", American Association for Cancer Research Annual Meeting 2015, Philadelphia, PA., 2015/04/22
"Genome-wide Mutational Signatures of Aristolochic Acid in Urothelial Cancer", 29th Annual EAU congress, Stockholm, 2014/04/11
"Simultaneously Detection of DNA bases at Graphene-NF Modified electrode", 國立臺北科技大學暨台北醫學大學與馬偕紀念醫院學術合作研究成果聯合發表會, TAIPEI, 2013/06/05
"Nod-like receptors family member- NLRC5 as a useful prognostic marker in renal cell carcinomas", AACR Annual Meeting 2013, Washington, DC, 2013/04/06
"The generation of tnfaip3 deficient Zebrafish model", 第二十八屆生物醫學聯合學術年會, Taipei, 2013/03/23
"High-level expression of miR-378 alters the sensitivity of Cetuximab response in KRAS/BRAF mutation colorectal cancer", 8th International Conference and Exhibition RNAi2013, St Hilda's College, Oxford, 2013/03/19
"Comparative analysis of TiO2 effect on DNA amplification reactions: in vitro", 2013中華民國高分子學會年會、第三十六屆高分子學術研討會暨國科會一百零一年度高分子學門成果發表會、奈米科技與生物高分子國際研討會, 嘉義縣, 2013/01/25
"Simultaneously detection of DNA bases at Graphene-NF modified electrode", 2012年中國化學年會, 台南市, 2012/12/01
"The colorectal cancer classifying platform for drug efficacy", 101年年會暨基因標記暨轉譯醫學應用研討會, 台南, 2012/06/02
"Gene Profiling of Cholangiocarcinoma Induced by Thioacetamide in a Rat Model", XGen Congress & Expo, San Diego, 2012/03/05
"Methylated DNA Profiling in Renal Cell Carcinoma", XGen Congress & Expo, San Diego, 2012/03/05
"Cytogenetic analysis on aberrations of chromosomal structure in diffuse large B-cell lymphoma", The Taiwan Society for Biochechemistry and Molecular Biology, Nantou, 2011/11/24
"Aberrent expression of PRAC gene in prostate cancer", Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB), Singapore, 2011/10/05
"Genetic alterations in intrahepatic cholangiocarcinoma-relvealed by array CGH, SKY and gene expression microarray", American Association for Cancer Research 102nd Annual Meeting, Orlando, FL, 2011/04/02
"Molecular cytogenetic study of cholangiocarcinoma", The Taiwan Society for Biochechemistry and Molecular Biology, Nantou, 2010/11/11
"Overexpression of enolase-α in lung cancer", The Taiwan Society for Biochechemistry and Molecular Biology, Nantou, 2010/11/11
"Analysis the Gene Status of MALToma by Using FISH and Array CGH", The Taiwan Society for Biochechemistry and Molecular Biology, Nantou, 2010/11/11
"Computational Analysis: Towards a Better Knowledge of the Molecular Evolution of Phosphoenolpyruvate Carboxylase among Flaveria Species", Convergence of Biomedical Science and Information Technologies (CBSIT 2010), Cebu, 2010/08/11
"microRNA expression patterns associated with resistance to platinum-based chemotherapy in human cancer cell lines", AACR 101st Annual Meeting 2010, Washington, DC, 2010/04/17
"Genomic comparison of different subtypes of renal cell carcinoma using SKY, CGH", AACR 101st Annual Meeting 2010, Washington, DC, 2010/04/17
"Analysis of HER gene family status in hepatocellular carcinoma by FISH", AACR 101st Annual Meeting 2010, Washington, DC, 2010/04/17
"Immunophenotyping xenotransplantability and molecular cytogenetic features of the sarcomatoid renal carcinoma cell line RCC52 : Pathobiological significance", AACR 101st Annual Meeting 2010, Washington, D.C., 2010/04/17
"Aberrant activation of ERBB3 oncogenic signaling in human hepatocellular carcinoma", AACR 101st Annual Meeting 2010, Washington, D.C., 2010/04/17
"The Role of Various Phosphorylation of Ezrin in c-kit Mutant Cancers", The 25th Joint annual conference of biomediacl science, Taipei, 2010/03/27
"Analysis Of Gene Expression In Drug-Resistant Cancer Cell Lines- By Using Array-Based Approaches", THE 25TH Joint Annual Conference of Biomedical science, Taipei, 2010/03/27
"Overexpression of Her3 in hepatocellular carcinoma", Biotechnology Taiwan 2009 – International Symposium on Stem Cell, Vaccine, and Molecular Medicine, Taiepi, 2009/11/06
"Differential response of primary or secondary exon 13 and exon 17 c-kit mutant to nilotinib and sunitinib – findings from a cell-based drug-screening platform", American Society of Clinical Oncology (ASCO) 45th Annual Meeting, Orlando, Florida, 2009/05/29
"Molecular characterization of acquired resistance to picropodophyllin (PPP),http://www.abstractsonline.com/viewer/viewAbstractPrintFriendly.asp?CKey={AB6025B6-CBA3-4F27-8572-1E0750104553}&SKey={00F20808-0B3A-416B-A024-4CA8BD03C371}&MKey={D007B270-E8F6-492", 2009 AACR Annual Meeting, Denver, CO, 2009/04/18
"Advantages and application of in situ hybridization technology on cancer research", 2009 Symposium on Biomedical Technology & Healthcare Management (BTHM2009), Taoyuan County, 2009/03/13
"Genetic abnormalities in gastric mucosa-associated lymphoid tissue lymphoma:Reveal by FISH, CGH and SKY", Second AACR Centennial Conference on Translational Cancer Medicine-- July 20-23, 2008, Monterey, CA, 2008/07/20
"Molecular cytogenetic analysis of bladder cancer by array-based comparative genomic hybridization and FISH", Second AACR Centennial Conference on Translational Cancer Medicine-- July 20-23, 2008, Monterey, CA, 2008/07/20
"Prognostic significance of ezrin protein expression in gastrointestinal stromal tumors in Taiwan", 2008 AACR Annual Meeting, San Diego, 2008/04/12
"Comparative analysis of genetic alterations associated with androgen-resistant prostate cancer transformation using SKY, CGH and c DNA microarray", 台灣泌尿科醫學會, 台北, 2005/09/01
"Association between immunohistochemical expression of ezrin and poor survival in soft tissue sarcomas", American Association for cancer research (AACR) 96th annual meeting. 2005/04/16-20, Anaheim, 2005/04/16
"Characterization of large chromosome markers in a malignant fibrous histiocytoma by SKY, CGH and array CGH", Marie-Curie Conferences and training courses on arrayCGH and molecular cytogenetics, Sanger institute, Cambridge., 2004/09/29
"Distinct pattern of chromosomal imbalances in intra-abdominal soft tissue sarcomas", American Association for cancer research (AACR) 95th annual meeting, Florida, 2004/03/27
"Molecular cytogenetic overview of soft tissue sarcomas", KI Cancer Conference Sandhamn, Stockholm, 2003/09/18
"DNA markers associated with improved survival in malignant fibrous histiocytoma", 8th European workshop on cytogenetics and molecular genetics of human solid tumors, Barcelona2002/09/12-15, 2002/09/12
